GITR Monoclonal Antibody

SKU: BT-MCA4444

Size:100μL

Background:This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Research_area:Others

Target_protein:GITR

applications:FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:6H8B9

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:GITR

Immunogen:Purified recombinant fragment of human GITR (AA: 184-241) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):26kDa

UniProt accession:Q9Y5U5

Synonyms:TNFRSF18, AITR, CD357, GITR-D

GeneID:8784