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GeneBio Systems

GEMIN2 Polyclonal Antibody

GEMIN2 Polyclonal Antibody

SKU:E-AB-12645

Regular price €338,95 EUR
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Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:GEMIN2

Target Synonym:Component of gems 2;Gem (nuclear organelle) associated protein 2;Gem associated protein 2;GEMI2;Gemin-2;gemin2;SIP 1;SIP-1;SIP1;SIP1 delta;SIP1-delta;SMN interacting protein 1;SMN interacting protein 1 delta;SMN-interacting protein 1;Survival interacting protein 1;Survival of motor neuron protein interacting protein 1;Survival of motor neuron protein-interacting protein 1

Research Areas:Cancer;Neuroscience;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:O14893

Accession:

Background:This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.

Concentration:0.1 mg/mL

Immunogen:Synthetic peptide of human GEMIN2

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:IHC 1:50-1:200

Calculated MW:

ObservedMW:

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