GAD1 Polyclonal Antibody

SKU: E-AB-17390

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: GAD1

Target Synonym: 67 kDa glutamic acid decarboxylase;CPSQ1;DCE1;DCE1;EC 4.1.1.15;FLJ45882;GAD 67;GAD;GAD-67;GAD1;Glutamate decarboxylase 1 (brain;67kDa);Glutamate decarboxylase 1;Glutamate decarboxylase 1 brain 67kD;Glutamate decarboxylase 1 brain 67kDa;Glutamate decarboxylase 67 kDa isoform;Glutamate decarboxylase;brain;67-KD;OTTHUMP00000041055;SCP

Research Areas: Cancer;Metabolism;Immunology;Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q99259

Accession:

Background: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.

Concentration: 0.2 mg/mL

Immunogen: Synthetic peptide of human GAD1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:200-1000;IHC 1:25-100

Calculated MW: 67 kDa

ObservedMW: