GABA A Receptor γ2 rabbit pAb

SKU: ES20747

Size: 100μL

Source:Rabbit

Applications:WB;IHC;IF

Reactivity:Human;Rat;Mouse

Dilution:WB 1:1000-2000, IHC 1:100-200

Immunogen:Synthetic Peptide of GABA A Receptor γ2

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):55kD

Human_gene_id:2566

Human_swiss_prot_no:P18507

Subcellular_location:Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Cell projection, dendrite . Cytoplasmic vesicle membrane .

Other_name:Gamma-aminobutyric acid receptor subunit gamma-2 (GABA(A) receptor subunit gamma-2)

Background:This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],