FZD6 Polyclonal Antibody

SKU: E-AB-12926

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: FZD6

Target Synonym: Frizzled 6 seven transmembrane spanning receptor;Frizzled drosophila homolog of 6;Frizzled family receptor 6;Frizzled homolog 6 (Drosophila);Frizzled homolog 6;Frizzled-6;Frizzled6;Fz 6;Fz-6;Fz6;FZD 6;Fzd6;FZD6;Hfz 6;hFz6;NDNC10

Research Areas: Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: O60353

Accession:

Background: This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.

Concentration: 0.2 mg/mL

Immunogen: Synthetic peptide of human FZD6

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:100-1:300

Calculated MW:

ObservedMW: