Frizzled-4 rabbit pAb

SKU: ES8800

Size: 100μL

Source:Rabbit

Applications:IHC;IF;ELISA

Reactivity:Human;Mouse;Rat

Dilution:IHC-p 1:50-200, ELISA 1:10000-20000

Immunogen:Synthetic peptide from human protein at AA range: 11-60

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:8322

Human_swiss_prot_no:Q9ULV1

Subcellular_location:Cell membrane ; Multi-pass membrane protein .

Other_name:Frizzled-4 (Fz-4;hFz4;FzE4;CD antigen CD344)

Background:frizzled class receptor 4(FZD4) Homo sapiens This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008],