FOLR1 antibody , Cat. # FNab03185

SKU: FNab03185

Size:100ug

Purification:Protein A+G purification

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Mouse

Clonality:monoclonal

Clone ID:6A8

Isotype:IgG1

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.

Immunogen:folate receptor 1

Synonyms:Adult folate binding protein, FBP, Folate receptor 1, folate receptor 1(adult), Folate receptor alpha, Folate receptor, adult, FOLR, FOLR1, FR alpha

Observed MW:38 kDa

Uniprot ID:P15328

Reactivity:Human

Tested Application:ELISA, WB,IHC

Recommended dilution:WB: 1:500-1:2000; IHC: 1:50-1:500

Gene ID:2348

Research Area:Immunology, Metabolism