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GeneBio Systems

FNIP2 Polyclonal Antibody

FNIP2 Polyclonal Antibody

SKU:E-AB-19877

Regular price €489,95 EUR
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Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: FNIP2

Target Synonym: FNIP1-like protein;Fnip2;FNIP2;FNIPL;Folliculin-interacting protein 2;KIAA1450;MAPO1;O6-methylguanine-induced apoptosis 1 protein;OTTHUMP00000221326

Research Areas: Cancer;Metabolism;Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: WB

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q9P278

Accession:

Background: This gene encodes a protein that binds to the tumor suppressor folliculin and to AMP-activated protein kinase (AMPK), and may play a role cellular metabolism and nutrient sensing by regulating the AMPK-mechanistic target of rapamycin signaling pathway. The encoded protein may also be involved in regulating the O6-methylguanine-induced apoptosis signaling pathway. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin.

Concentration: 1.14 mg/mL

Immunogen: Synthetic peptide of human FNIP2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 122 kDa

ObservedMW: Refer to figures

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