Fluor® 647 Anti-Mouse TNFα Antibody[XT3.11]

SKU: AN00567M

Size:100Tests

Storage:This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:TNF-α

Target Synonym:Tumor necrosis factor-α;Cachectin;Necrosin;Macrophage cytotoxic factor;Differentiation inducing factor;TNFSF-2;TNF-a;TNF-alpha

Research Areas:

Conjugation:Elab Fluor®647

Host:Rat

Species reactivity:Mouse

Application:ICFCM

Usage:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Isotype:Rat IgG1, κ

Clonality:Monoclonal

Clone NO.:XT3.11

UNIProt ID:P06804

Background:TNF-α is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells. Many transformed cell lines also secrete TNF-α. Monomeric mouse TNF-α is a 156 amino acid protein (N-glycosylated) with a reported molecular weight of 17.5 kD. TNF-α forms multimeric complexes; stable trimers are most common in solution. A 26 kD membrane form of TNF-α has also been described. TNF-α binding to surface receptors elicits a wide array of biologic activities including: cytolysis and cytostasis of many tumor cell lines in vitro, hemorrhagic necrosis of tumors in vivo, increased fibroblast proliferation, and enhanced chemotaxis and phagocytosis in neutrophils.

Concentration:5 μL/Test

Control catalog number:E-AB-F09822M

Immunogen:

Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant

Purification method:

Dilution:

GeneID:21926