FKBP5 Polyclonal Antibody

SKU: E-AB-17966

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: FKBP5

Target Synonym: 51 kDa FK506 binding protein 5;51 kDa FK506 binding protein;51 kDa FK506-binding protein;51 kDa FKBP;54 kDa progesterone receptor associated immunophilin;54 kDa progesterone receptor-associated immunophilin;AIG 6;AIG6;Androgen regulated protein 6;Androgen-regulated protein 6;FF1 antigen;FK506 binding protein 5;FK506-binding protein 5;FKBP 5;FKBP 51;FKBP 54;FKBP-5;FKBP-51;FKBP5;FKBP5;FKBP54;HSP90 binding immunophilin;HSP90-binding immunophilin;MGC111006;OTTHUMP00000016268;P54;Peptidyl prolyl cis trans isomerase;Peptidyl-prolyl cis-trans isomerase FKBP5;Peptidylprolyl cis trans isomerase;PPIase;PPIase FKBP5;Ptg 10;Ptg10;Rotamase;T cell FK506 binding protein

Research Areas: Cancer;Immunology;Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q13451

Accession:

Background: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.

Concentration: 1.5 mg/mL

Immunogen: Synthetic peptide of human FKBP5

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000;IHC 1:50-1:300

Calculated MW: 51 kDa

ObservedMW: Refer to figures