FH/Fumarase Rabbit pAb

SKU: EA022

Size: 100μL

Source:Rabbit

Applications:WB, IF

Reactivity:Human, Rat, Mouse

Dilution:WB 1:1,000

Immunogen:Recombinant Protein

Storage_stability:PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality:Polyclonal

Isotype:IgG

Concentration:1mg/mL

Observed_band(KD):50kDa

Human_gene_id:2271

Human_swiss_prot_no:P07954

Subcellular_location:

Other_name:Fumarase, fumarate hydratase, HLRCC, LRCC, MCL, MCUL1

Background:Fumarase (FH) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to malate in the mitochondria. Fumarase deficiency is caused by a mutation in the fumarase gene in humans. Fumarase deficiency is one of the few known deficiencies of the Krebs cycle or tricarboxylic acid cycle, the main enzymatic pathway of cellular aerobic respiration.