FCMR Antibody - Cat. #: CSB-PA007972ESR2HU

SKU: CSB-PA007972ESR2HU

Size :50ul

Clone Number:

Aliases:Faim3 antibody; FAIM3_HUMAN antibody; Fas apoptotic inhibitory molecule 3 antibody; Fc fragment of IgM receptor antibody; Fc mu receptor antibody; FCMR antibody; IgM Fc receptor antibody; Immunoglobulin mu Fc receptor antibody; Regulator of Fas induced apoptosis antibody; Regulator of Fas-induced apoptosis Toso antibody; TOSO antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O60667

Immunogen:Recombinant Human Fas apoptotic inhibitory molecule 3 protein (18-251AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FCMR

Research Areas:Cell biology