FAT2 rabbit pAb

SKU: ES11838

Size: 100μL

Source:Rabbit

Applications:IHC;IF

Reactivity:Human;Mouse;Rat

Dilution:IHC-p 1:50-300

Immunogen:Synthesized peptide derived from part region of human protein

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):478kD

Human_gene_id:2196

Human_swiss_prot_no:Q9NYQ8

Subcellular_location:Cell membrane ; Single-pass type I membrane protein . Cell junction . Golgi apparatus, trans-Golgi network . Localized at adhesion zippers (early state of adherens junctions) of keratinocytes. .

Other_name:

Background:This gene is the second identified human homolog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has two epidermal growth factor (EGF)-like repeats and one laminin G domain. This protein most likely functions as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development. [provided by RefSeq, Jul 2008],