EYA4 Antibody, Biotin conjugated - Cat. #: CSB-PA007909LD01HU

SKU: CSB-PA007909LD01HU

Size :50ug

Clone Number:

Aliases:CMD1J antibody; Deafness, autosomal dominant 10 antibody; DFNA 10 antibody; DFNA10 antibody; dJ78N10.1 (eyes absent (Drosophila) homolog 4) antibody; dJ78N10.1 (eyes absent) antibody; EYA 4 antibody; eya4 antibody; EYA4_HUMAN antibody; Eyes absent 4 antibody; Eyes absent homolog 4 (Drosophila) antibody; Eyes absent homolog 4 antibody; HGNC:3522 antibody; OTTHUMP00000040267 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O95677

Immunogen:Recombinant Human Eyes absent homolog 4 protein (153-224AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Tyrosine phosphatase that specifically dephosphorylates \'Tyr-142\' of histone H2AX (H2AXY142ph). \'Tyr-142\' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. May be involved in development of the eye (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:EYA4

Research Areas:Epigenetics and Nuclear Signaling; Neuroscience; Cardiovascular