Exo1 rabbit pAb

SKU: ES2309

Size: 100μL

Source:Rabbit

Applications:WB;IF;ELISA

Reactivity:Human;Mouse

Dilution:Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Immunogen:The antiserum was produced against synthesized peptide derived from human EXO1. AA range:61-110

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):94kD

Human_gene_id:9156

Human_swiss_prot_no:Q9UQ84

Subcellular_location:Nucleus . Colocalizes with PCNA to discrete nuclear foci in S-phase.

Other_name:EXO1; EXOI; HEX1; Exonuclease 1; hExo1; Exonuclease I; hExoI

Background:This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms. [provided by RefSeq, Jul 2008],