ELF4 Antibody - Cat. #: CSB-PA857453ESR2HU

SKU: CSB-PA857453ESR2HU

Size :50ul

Clone Number:

Aliases:E74-like factor 4 antibody; ELF4 antibody; ELF4_HUMAN antibody; ELFR antibody; ETS-related transcription factor Elf-4 antibody; ETS-related transcription factor Elf4 antibody; MEF antibody; Myeloid Elf-1-like factor antibody; Myeloid Elf1-like factor antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q99607

Immunogen:Recombinant Human ETS-related transcription factor Elf-4 protein (1-200AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Transcriptional activator that binds to DNA sequences containing the consensus 5\\\'-WGGA-3\\\'. Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. Acts synergistically with RUNX1 to transactivate the IL3 promoter (By similarity). Also transactivates the PRF1 promoter in natural killer (NK) cells. Plays a role in the development and function of NK and NK T-cells and in innate immunity. Controls the proliferation and homing of CD8+ T-cells via the Kruppel-like factors KLF4 and KLF2 (By similarity). Controls cell senescence in a p53-dependent manner. Can also promote cellular transformation through inhibition of the p16 pathway.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ELF4

Research Areas:Epigenetics and Nuclear Signaling; Cancer