EDN1 Monoclonal Antibody

SKU: BT-MCA2424

Size:100μL

Background:This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.

Research_area:Signal Transduction

Target_protein:EDN1

applications:ICC, FCM

Reactivity:Human, Mouse

Clonality:Monoclonal

Clone ID:4E6E5

Host:Mouse

Isotype:Mouse IgG2a

Gene Symbol/ Name:EDN1

Immunogen:Purified recombinant fragment of human EDN1 (AA: 18-212) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):24.4KDa

UniProt accession:P05305

Synonyms:ET1, QME, PPET1, ARCND3, HDLCQ7

GeneID:1906