DYRK3 Polyclonal Antibody

SKU: BT-AP08670

Size:100μL

Background:This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified.

Research_area:Cardiovascular; Epigenetics and nuclear signaling; Stem cells

Target_protein:DYRK3

applications:WB, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Dual specificity tyrosine-phosphorylation-regulated kinase 3

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: O43781; Mouse: Q922Y0; Rat: Q4V8A3

Synonyms:Dual specificity tyrosine-phosphorylation-regulated kinase 3 ;EC 2.7.12.1;Regulatory erythroid kinase;REDK

GeneID:Human: 8444