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GeneBio Systems

DUSP22 Polyclonal Antibody

DUSP22 Polyclonal Antibody

SKU:E-AB-14065

Regular price €493,95 EUR
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Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: DUSP22

Target Synonym: Dual specificity protein phosphatase 22;DUS22;Dusp22;JNK stimulatory phosphatase 1;JNK-stimulatory phosphatase-1;JSP 1;JSP-1;JSP1;LMW DSP2;LMW-DSP2;Low molecular weight dual specificity phosphatase 2;MAP kinase phosphatase x;Mitogen activated protein kinase phosphatase x;Mitogen-activated protein kinase phosphatase x;MKP-x;MKPX

Research Areas: Cell Biology;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q9NRW4

Accession:

Background: Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP22 dephosphorylates ERK2 MAP kinase and JNK. DUSP22 displays highest in thymus, but it is also detectable in monocytes and lymphocytes.

Concentration: 0.4 mg/mL

Immunogen: Recombinant protein of human DUSP22

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:50-1:200

Calculated MW:

ObservedMW:

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