DRP1(Phospho-Ser616) Rabbit Polyclonal Antibody

SKU: BT-AP02311

Size:100μL

Background:This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division| and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders| including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder| encephalopathy| lethal| due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.

Research_area:Cancer; Cell biology; Metabolism; Neuroscience; Signal transduction

Target_protein:DNM1L

applications:WB

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:DRP1

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: O00429; Mouse: Q8K1M6; Rat: O35303

Synonyms:DRP1 (Ser616) ; Dynamin-1-like protein; EC 3.6.5.5; Dnm1p/Vps1p-like protein; DVLP; Dynamin family member proline-rich carboxyl-terminal domain less; Dymple; Dynamin-like protein; Dynamin-like protein 4; Dynamin-like protein IV; HdynIV; Dynamin-related protein 1)

GeneID:Human: 10059; Mouse: 74006; Rat: 114114