DOK1 Antibody - Cat. #: CSB-PA040823

SKU: CSB-PA040823

Size :50ul

Clone Number:

Aliases:Docking protein 1 62kD antibody; Docking protein 1 antibody; DOK 1 antibody; DOK1 antibody; DOK1_HUMAN antibody; Downstream of tyrosine kinase 1 antibody; p62(dok) antibody; P62DOK antibody; pp62 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q99704

Immunogen:Fusion protein of Human DOK1

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; ELISA:1:2000-1:5000, WB:1:500-1:2000

Background:The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Two transcript variants encoding different isoforms have been found for this gene. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:DOK1

Research Areas:Cancer?Cardiovascular;Metabolism;Signal transduction