DGCR8 Rabbit Polyclonal Antibody

SKU: BT-AP09158

Size:100μL

Background:This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein| Drosha. Alternate splicing results in multiple transcript variants.

Research_area:Epigenetics and nuclear signaling

Target_protein:DGCR8

applications:WB

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:DGCR8

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q8WYQ5; Mouse: Q9EQM6

Synonyms:DGCR8; Microprocessor complex subunit DGCR8; DiGeorge syndrome critical region 8)

GeneID:Human: 54487; Mouse: 94223