DENND1B Polyclonal Antibody

SKU: E-AB-18656

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: DENND1B

Target Synonym: C1ORF18;C1orf218 ;Chromosome 1 open reading frame 218;Connecdenn 2;DEN1B;DENN domain containing protein 1B;DENN domain-containing protein 1B;DENN MADD domain containing 1B;DENND1B;DKFZp547O0715;FAM31B ;Family with sequence similarity 31 member B;FLJ20054;FLJ21179 ;FLJ33888;MGC103810;MGC27044;Protein FAM31B;RP11 53I24.2

Research Areas: Cell Biology

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q6P3S1

Accession:

Background: Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery.

Concentration: 0.54 mg/mL

Immunogen: Fusion protein of human DENND1B

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 86 kDa

ObservedMW: Refer to figures