DCTN3 Rabbit Polyclonal Antibody

SKU: BT-AP09074

Size:100μL

Background:This gene encodes the smallest subunit of dynactin| a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions| including ER-to-Golgi transport| the centripetal movement of lysosomes and endosomes| spindle formation| cytokinesis| chromosome movement| nuclear positioning| and axonogenesis. This subunit| like most other dynactin subunits| exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil| and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants.

Research_area:Cell biology; Signal transduction

Target_protein:DCTN3

applications:WB

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:DCTN3

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):20460

UniProt accession:Human: O75935; Mouse: Q9Z0Y1

Synonyms:DCTN3

GeneID:Human: 11258; Mouse: 53598