1 1

Gene Bio Systems

CYR61 Antibody - Cat. #: CSB-PA940403

CYR61 Antibody - Cat. #: CSB-PA940403

CSB-PA940403

€329,95 EUR
€329,95 EUR
Sale Sold out
Shipping calculated at checkout.

Size :50ug

Clone Number:

Aliases:3CH61 antibody; CCN 1 antibody; CCN family member 1 antibody; CCN1 antibody; CYR 61 antibody; Cyr61 antibody; CYR61 protein antibody; CYR61_HUMAN antibody; Cysteine rich angiogenic inducer 61 antibody; Cysteine rich heparin binding protein 61 antibody; Cysteine-rich angiogenic inducer 61 antibody; GIG 1 antibody; GIG1 antibody; IBP-10 antibody; IGF-binding protein 10 antibody; Igfbp 10 antibody; IGFBP-10 antibody; Igfbp10 antibody; Insulin like growth factor binding protein 10 antibody; Insulin-like growth factor-binding protein 10 antibody; Protein CYR61 antibody; Protein GIG1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O00622

Immunogen:CYR61 Polyclonal Antibody detects endogenous levels of protein.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:WB, ELISA; WB:1:500-1:2000, ELISA:1:10000

Background:Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CCN1

Research Areas:Others

View full details