CYP3A4 Antibody - Cat. #: CSB-PA006439LA01HU

SKU: CSB-PA006439LA01HU

Size :50ug

Clone Number:

Aliases:1,8-cineole 2-exo-monooxygenase antibody; Albendazole monooxygenase antibody; Albendazole sulfoxidase antibody; CP33 antibody; CP34 antibody; CP3A4_HUMAN antibody; CYP3 antibody; CYP3A antibody; CYP3A3 antibody; CYP3A4 antibody; CYPIIIA3 antibody; CYPIIIA4 antibody; Cytochrome P450 3A3 antibody; Cytochrome P450 3A4 antibody; Cytochrome P450 family 3 subfamily A polypeptide 4 antibody; Cytochrome P450 HLp antibody; Cytochrome P450 NF-25 antibody; Cytochrome P450 subfamily IIIA polypeptide 4 antibody; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3 antibody; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 antibody; Cytochrome P450-PCN1 antibody; Glucocorticoid inducible P450 antibody; HLP antibody; MGC126680 antibody; NF 25 antibody; NF25 antibody; Nifedipine oxidase antibody; P450 III steroid inducible antibody; P450 PCN1 antibody; P450, family III antibody; P450C3 antibody; P450PCN1 antibody; Quinine 3 monooxygenase antibody; Quinine 3-monooxygenase antibody; Taurochenodeoxycholate 6 alpha hydroxylase antibody; Taurochenodeoxycholate 6-alpha-hydroxylase antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P08684

Immunogen:Recombinant Human Cytochrome P450 3A4 protein (259-441AA)

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC, IF; Recommended dilution: WB:1:200-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Background:Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1\\\'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2-exo-monooxygenase. The enzyme also hydroxylates etoposide (PubMed:11159812). Catalyzes 4-beta-hydroxylation of cholesterol. May catalyze 25-hydroxylation of cholesterol in vitro (PubMed:21576599).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CYP3A4

Research Areas:Cancer; Cardiovascular; Metabolism; Signal transduction