CYP1A2 Antibody, FITC conjugated - Cat. #: CSB-PA006396LC01HU

SKU: CSB-PA006396LC01HU

Size :50ug

Clone Number:

Aliases:Aryl hydrocarbon hydroxylase antibody; CP 12 antibody; CP12 antibody; CP1A2_HUMAN antibody; CYP1A2 antibody; CYPIA2 antibody; Cytochrome P(3)450 antibody; Cytochrome P450 1A2 antibody; Cytochrome P450 4 antibody; Cytochrome P450 family 1 polypeptide 2 antibody; Cytochrome P450 family 1 subfamily A polypeptide 2 antibody; Cytochrome P450 subfamily I aromatic compound inducible polypeptide 2 antibody; Cytochrome P450-P3 antibody; Cytochrome P4501A2 antibody; Dioxin inducable P3 450 antibody; Flavoprotein linked monooxygenase antibody; Flavoprotein-linked monooxygenase antibody; Microsomal monooxygenase antibody; P(3)450 antibody; P3 450 antibody; P450 4 antibody; P450 form 4 antibody; P450 P3 antibody; P450(PA) antibody; Xenobiotic monooxygenase antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P05177

Immunogen:Recombinant Human Cytochrome P450 1A2 protein (268-445AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CYP1A2

Research Areas:Cancer; Cardiovascular; Metabolism; Signal transduction