CTTN Monoclonal Antibody

SKU: BT-MCA3466

Size:100μL

Background:This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. (provided by RefSeq)

Research_area:Signal Transduction

Target_protein:CTTN

applications:WB, IHC

Reactivity:Human, Mouse

Clonality:Monoclonal

Clone ID:4C6

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:CTTN

Immunogen:Purified recombinant fragment of human CTTN expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):80kDa

UniProt accession:Q14247

Synonyms:EMS1, FLJ34459, CTTN

GeneID:2017