CtBP1/2(Phospho Ser158/164) Rabbit Polyclonal Antibody

SKU: BT-AP01991

Size:100μL

Background:cofactor:NAD. Required for efficient interaction with E1A. Cofactor binding induces a conformation change.|Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex (By similarity). Co-repressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity.|PTM:ADP-ribosylated; when cells are exposed to brefeldin-A (BFA).|PTM:Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4.|PTM:The level of phosphorylation appears to be regulated during the cell cycle. Phosphorylated upon DNA damage| probably by ATM or ATR. Phosphorylation by HIPK2 on Ser-422 induces proteasomal degradation.|Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|subunit:Interacts with the C-terminus of adenovirus E1A protein| ELK3 and CTIP via their consensus motif P-X-

Research_area:Cancer; Cell biology; Epigenetics and nuclear signaling; Microbiology

Target_protein:CTBP1

applications:WB, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:CtBP1/2

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):48400

UniProt accession:Human: Q13363/P56545; Mouse: O88712; Rat: Q9Z2F5

Synonyms:CtBP1/2 ;Phospho Ser158/164; C-terminal-binding protein 1; CtBP1; EC 1.1.1.-

GeneID:Human: 1487; Mouse: 13016; Rat: 29382