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GeneBio Systems

CSTB Polyclonal Antibody

CSTB Polyclonal Antibody

SKU:E-AB-13179

Regular price €493,95 EUR
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Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: CSTB

Target Synonym: CHROW21;CPI B;CPI-B;CST 6;CST6;CSTB;Cystatin B (stefin B);Cystatin B;Cystatin-B;CYTB;CYTB;EPM1;EPM1A;Liver thiol proteinase inhibitor;PME;Stefin-B;STF B;STFB;ULD

Research Areas: Cancer;Cell Biology

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P04080

Accession:

Background: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1).

Concentration: 0.9 mg/mL

Immunogen: Synthetic peptide of human CSTB

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:50-1:200

Calculated MW:

ObservedMW:

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