CSH1 rabbit pAb

SKU: ES8539

Size: 100μL

Source:Rabbit

Applications:WB;IHC;IF;ELISA

Reactivity:Human;Rat;Mouse;

Dilution:IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000

Immunogen:Synthetic peptide from human protein at AA range: 161-210

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):25kD

Human_gene_id:1442

Human_swiss_prot_no:P01243

Subcellular_location:extracellular region,endoplasmic reticulum,vesicle,membrane-bounded vesicle,

Other_name:CSH1; CSH2

Background:The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, al