CP2C9 Polyclonal Antibody

SKU: BT-AP08039

Size:100μL

Background:This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.

Research_area:Cardiovascular; Metabolism; Signal transduction

Target_protein:CYP2C9

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Cytochrome P450 2C9

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: P11712

Synonyms:Cytochrome P450 2C9 ;EC 1.14.13.-;;R-limonene 6-monooxygenase;EC 1.14.13.80;;S-limonene 6-monooxygenase;EC 1.14.13.48;;S-limonene 7-monooxygenase;EC 1.14.13.49;CYPIIC9;Cytochrome P-

GeneID:Human: 1559