GeneBio Systems
COX17 Polyclonal Antibody
COX17 Polyclonal Antibody
SKU:E-AB-19376
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Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: COX17
Target Synonym: COX 17;COX17;COX17 cytochrome c oxidase assembly homolog (S. cerevisiae);COX17 cytochrome c oxidase assembly homolog;COX17 homolog cytochrome c oxidase assembly protein;COX17;cytochrome c oxidase assembly protein cox17 homolog;Cytochrome c oxidase copper chaperone;Human homolog of yeast mitochondrial copper recruitment;MGC104397;MGC117386;OTTHUMP00000215284;OTTHUMP00000215285
Research Areas: Cancer;Metabolism;Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human;Mouse
Application: IHC
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: Q14061
Accession:
Background: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13.
Concentration: 1.2 mg/mL
Immunogen: Synthetic peptide of human COX17
Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification method: Antigen affinity purification
Dilution: IHC 1:30-1:150
Calculated MW:
ObservedMW:
