COL18A1 Polyclonal Antibody

SKU: E-AB-70197

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:COL18A1

Target Synonym:Antiangiogenic agent;COIA1;Col18a1;Collagen alpha 1(XVIII) chain;Collagen type XVIII alpha 1;Endostatin;KNO;KNO1;KS;Multi functional protein MFP

Research Areas:Cancer;Cardiovascular;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P39060,P39061

Accession:

Background:This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Concentration:1.1 mg/mL

Immunogen:KLH conjugated Synthetic peptide corresponding to Mouse Endostatin

Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification method:Affinity purification

Dilution:IHC 1:300-1:1000

Calculated MW:

ObservedMW: