CERS4 Antibody - Cat. #: CSB-PA054139

SKU: CSB-PA054139

Size :50ul

Clone Number:

Aliases:ceramide synthase 4 antibody; CerS4 antibody; FLJ12089 antibody; LAG1 homolog ceramide synthase 4 antibody; LAG1 longevity assurance homolog 4 antibody; LAG1, S. cerevisiae, homolog of, 4 antibody; LASS 4 antibody; LASS4 antibody; LASS4 LAG1 homolog ceramide synthase 4 antibody; LASS4_HUMAN antibody; TRAM homolog 1 antibody; Trh 1 antibody; Trh1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9HA82

Immunogen:Synthetic peptide of Human CERS4

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200

Background:The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they are all involved in sphingolipid synthesis. LASS4 is a 394 amino acid endoplasmic reticulum, multi-pass membrane protein. LASS4 increases the levels of long ceramides such as C22:0- and C24:0-ceramides. In cells deficient for CLN9, as observed in neuronal ceroid lipofuscinosis (NCL) or Batten disease, LASS4 can increase ceramide levels and partially correct growth and apoptosis.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CERS4

Research Areas:Cancer;Metabolism;Signal transduction