CDK8 Antibody - Cat. #: CSB-PA162953

SKU: CSB-PA162953

Size :50ul

Clone Number:

Aliases:cdk8 antibody; CDK8 protein kinase antibody; CDK8_HUMAN antibody; Cell Division Kinase 8 antibody; Cell division protein kinase 8 antibody; Cyclin Dependent kinase 8 antibody; Cyclin-dependent kinase 8 antibody; K35 antibody; Mediator complex subunit cdk8 antibody; Mediator of RNA polymerase II transcription subunit cdk8 antibody; Protein kinase K35 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P49336

Immunogen:Synthetic peptide of Human CDK8

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100

Background:The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CDK8

Research Areas:Epigenetics and Nuclear Signaling;Cell biology