CDH23 Antibody - Cat. #: CSB-PA094215

SKU: CSB-PA094215

Size :100ul

Clone Number:

Aliases:CDH23 antibody; KIAA1774 antibody; KIAA1812 antibody; UNQ1894/PRO4340Cadherin-23 antibody; Otocadherin antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9H251

Immunogen:Synthetic peptide corresponding to residues near the C terminal of Human pan-cadherin

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; IHC:1:50-1:100

Background:This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CDH23

Research Areas:Neuroscience;Signal transduction