CD8 Monoclonal Antibody

SKU: BT-MCA2729

Size:100μL

Background:CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds .It belongs type I membrane protein. Selectively expressing of CD8 on a subset of T cells leads to CD8 T cell development. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine-protein kinase p56lck.

Research_area:Others

Target_protein:CD8

applications:FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:RAVB3

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:CD8

Immunogen:Purified recombinant fragment of human CD8 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):

UniProt accession:P01732

Synonyms:MAL, p32, Leu2, CD8A

GeneID:925