CD39 antibody , Cat. # FNab01474

SKU: FNab01474

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:ENTPD1(Ectonucleoside triphosphate diphosphohydrolase 1) is also named as CD39, NTPDase 1, Ecto-ATPDase 1 and belongs to the GDA1/CD39 NTPase family. In the nervous system, it can hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission.It is a noncovalent tetrameric protein and that detergent inhibition of enzymatic activity is caused by dissociation of ectoapyrase tetramers into monomers(PMID: 9733785).And it is a 70-to 100-kDa protein that is heavily N-glycosylated(PMID:7930580). It has 3 isoforms produced by alternative splicing. CD39 preferentially occurred as a dimer that could be dissociated into monomeric forms.(PMID: 12694193). The soluble isoform of CD39(38-478 amino acid) locates to the extracellular part and FNab01474 recognizes both the 3 isoforms and soluble form of CD39(38-478aa) molecule.

Immunogen:ectonucleoside triphosphate diphosphohydrolase 1

Synonyms:ATPDase, CD39, DKFZp686D194, DKFZp686I093, Ecto apyrase, Ecto ATP diphosphohydrolase 1, Ecto ATPase 1, Ecto ATPDase 1, ENTPD1, FLJ40921, FLJ40959, NTPDase 1

Observed MW:75-95 kDa

Uniprot ID:P49961

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC, FC, IP

Recommended dilution:WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

Gene ID:

Research Area:Stem Cells, Immunology, Metabolism, Cancer