CD178 Monoclonal Antibody

SKU: BT-MCA3829

Size:100μL

Background:This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.

Research_area:Others

Target_protein:CD178

applications:ICC, FCM

Reactivity:

Clonality:Monoclonal

Clone ID:2A6E12

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:CD178

Immunogen:Purified recombinant fragment of human CD178 (AA: extra 103-281) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):31.5kDa

UniProt accession:P48023

Synonyms:FASLG, APTL, FASL, CD95L, ALPS1B, CD95-L, TNFSF6, TNLG1A, APT1LG1

GeneID:356