CD163 Monoclonal Antibody

SKU: AN200059P

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Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies

Abbreviation:CD163

Target Synonym:GHI/;SCARI;CD163;M130;MM130;SCARI1;ED2(rat);GHI/61;Hemoglobin/Haptoglobin Complex Receptor;macrophage-associated antigen;p155;RM3/1;GHI/61

Research Areas:Immunology;Cardiovascular

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:IHC-P

Isotype:IgG1

Clonality:Monoclonal

Clone NO.:9D12

UNIProt ID:Q86VB7

Accession:

Background:The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Concentration:1 mg/mL

Immunogen:E. coli-derived Human CD163 fragment

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:IHC-P 1:2000-1:10000;

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ObservedMW: