CD120B Monoclonal Antibody

SKU: BT-MCA4042

Size:100μL

Background:The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.

Research_area:Others

Target_protein:CD120B

applications:FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:7G8B6

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:CD120B

Immunogen:Purified recombinant fragment of human CD120B (AA: extra 23-257) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):48.3kDa

UniProt accession:P20333

Synonyms:TNFRSF1B, p75, TBPII, TNFBR, TNFR2, TNFR1B, TNFR80, TNF-R75, p75TNFR, TNF-R-II

GeneID:7133