CD11B Polyclonal Antibody

SKU: E-AB-60354

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:CD11B

Target Synonym:CD11B;CR3A;MAC-1;MAC1A;MO1A;SLEB6;ITGAM;CD11b/ITAM

Research Areas:Cancer;Neuroscience;Signal Transduction;Stem Cells;Tags and Cell Markers

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:IF

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P11215

Accession:

Background:This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.

Concentration:1mg/mL

Immunogen:Recombinant fusion protein of human CD11B (NP_001139280.1).

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification method:Affinity purification

Dilution:IF 1:50-1:200

Calculated MW:

ObservedMW: