CD108 rabbit pAb

SKU: ES8677

Size: 100μL

Source:Rabbit

Applications:IHC;IF;ELISA

Reactivity:Human;Mouse;Rat

Dilution:IHC-p 1:50-200, ELISA 1:10000-20000

Immunogen:Synthetic peptide from human protein at AA range: 101-150

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:8482

Human_swiss_prot_no:O75326

Subcellular_location:Cell membrane ; Lipid-anchor, GPI-anchor ; Extracellular side . Detected in a punctate pattern on the cell membrane of basal and supra-basal skin keratinocytes.

Other_name:Semaphorin-7A (CDw108;JMH blood group antigen;John-Milton-Hargen human blood group Ag;Semaphorin-K1;Sema K1;Semaphorin-L;Sema L;CD antigen CD108)

Background:This gene encodes a member of the semaphorin family of proteins. The encoded preproprotein is proteolytically processed to generate the mature glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein. The encoded protein is found on activated lymphocytes and erythrocytes and may be involved in immunomodulatory and neuronal processes. The encoded protein carries the John Milton Hagen (JMH) blood group antigens. Mutations in this gene may be associated with reduced bone mineral density (BMD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016],