CCR5 Polyclonal Antibody

SKU: E-AB-70361

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:CCR5

Target Synonym:AM4 7;C C chemokine receptor type 5;C C CKR 5;C-C chemokine receptor type 5;C-C CKR-5;C-C motif chemokine receptor 5 A159A;CC Chemokine Receptor 5;CC Chemokine Receptor Type 5;CC CKR 5;CC-CKR-5;CCCKR 5;CCCKR5;CCR 5;CCR-5;CCR5;CCR5 chemokine (C C motif) receptor 5;CCR5;CD 195;CD195;CD195 Antigen;Chemokine C C motif receptor 5;Chemokine receptor CCR5;CHEMR13;CKR 5;CKR5;CMKBR 5;CMKBR5;FLJ78003;HIV 1 Fusion Coreceptor;HIV-1 fusion coreceptor;HIV1 fusion coreceptor;IDDM22;MIP-1 alpha receptor

Research Areas:Cancer;Cardiovascular;Immunology;Microbiology;Neuroscience;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Mouse;Rat

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P51682,O08556

Accession:

Background:This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation.

Concentration:0.55 mg/mL

Immunogen:KLH conjugated Synthetic peptide corresponding to Mouse CCR5

Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification method:Affinity purification

Dilution:IHC 1:200-1:800

Calculated MW:

ObservedMW: