CBX3 Polyclonal Antibody

SKU: E-AB-12511

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:CBX3

Target Synonym:CBX 3;CBX3;CBX3;Chromobox homolog 3 (HP1 gamma homolog;Drosophila);Chromobox homolog 3;Chromobox protein homolog 3;GAMMA;HECH;Heterochromatin like protein 1;Heterochromatin protein 1 homolog gamma;Heterochromatin protein HP1 gamma;HP1 gamma;HP1 gamma homolog;HP1Hs gamma;Modifier 2 protein

Research Areas:Cancer;Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB;IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q13185

Accession:

Background:At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks.

Concentration:0.2 mg/mL

Immunogen:Synthetic peptide of human CBX3

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:WB 1:500-1:2000;IHC 1:50-1:200

Calculated MW:21kDa

ObservedMW: