GeneBio Systems
CBR1 Polyclonal Antibody
CBR1 Polyclonal Antibody
SKU:E-AB-10951
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Size::120μL
Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date:12 months
Category ID_II:Primary Antibodies
Category ID_III:Polyclonal Antibodies
Abbreviation:CBR1
Target Synonym:15 hydroxyprostaglandin dehydrogenase [NADP+];15-hydroxyprostaglandin dehydrogenase [NADP+];Carbonyl reductase [NADPH] 1;Carbonyl Reductase 1;CBR 1;CBR1;CBR1;CRN;NADPH dependent carbonyl reductase 1;NADPH-dependent carbonyl reductase 1;Prostaglandin 9 ketoreductase;Prostaglandin 9-ketoreductase;Prostaglandin E(2) 9 reductase;Prostaglandin-E(2) 9-reductase;SDR21C1
Research Areas:Cancer;Cell Biology;Metabolism;Signal Transduction
Conjugation:Unconjugated
Host:Rabbit
Species reactivity:Human;Mouse;Rat
Application:WB;IHC
Isotype:IgG
Clonality:Polyclonal
Clone NO.:
UNIProt ID:P16152
Accession:
Background:Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q. NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol.
Concentration:0.3 mg/mL
Immunogen:Recombinant protein of human CBR1
Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method:Affinity purification
Dilution:WB 1:1000-1:5000;IHC 1:50-1:200
Calculated MW:30kDa
ObservedMW:
