CAV2 Monoclonal Antibody

SKU: BT-MCA2081

Size:100μL

Background:The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. This gene and related family member (CAV1) are located next to each other on chromosome 7, and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described, and shown to have preferential localization in the cell (PMID:11238462).

Research_area:Tags & Cell Markers, Cardiovascular

Target_protein:CAV2

applications:WB, IHC, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:5E9E2

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:CAV2

Immunogen:Purified recombinant fragment of human CAV2 (AA: 1-86) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide.

Concentration:

Molecular weight(Da):18.3kDa

UniProt accession:P51636

Synonyms:CAV

GeneID:858