Canine calreticulin,CALR ELISA KIT

SKU: E0474Ca

Size:96 Tests-1 Kit

Background:Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle (PubMed:1915668). This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and might participate in the block to polyspermy (By similarity). {ECO:0000250|UniProtKB:P27797, ECO:0000250|UniProtKB:P28491, ECO:0000250|UniProtKB:Q8K3H7, ECO:0000269|PubMed:1915668}.

Research_area:

Applications:ELISA

Target_protein:CALR

Reactivity:Canine

Assay type:Sandwich

Sensitivity:0.02ng/ml

Detection range:0.05-35ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:calreticulin

Species:Canine

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P28490

MASS(Da):2855

GeneID:

Synonyms:CALR

Gene names:CALR

Standard solution:40ng/ml