Canine C-C Motif Chemokine 5, CCL5 ELISA Kit

SKU: E0337Ca

Size:96 Tests-1 Kit

Background:Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells.

Research_area:Immunology; Cardiovascular

Applications:ELISA

Target_protein:CCL5

Reactivity:Canine

Assay type:Sandwich

Sensitivity:0.021ng/mL

Detection range:0.05-20ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:C-C Motif Chemokine 5

Species:Canine

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8HYS0

MASS(Da):10,179

GeneID:403522

Synonyms:C-C motif chemokine 5;CCL 5;CCL5;Small-inducible cytokine A5;T-cell-specific protein RANTES

Gene names:CCL5

Standard solution:24ng/mL